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General Search of Food Request Database. IR-4 Food Use Request.
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PR#PriorityPesticide(MFG)Commodity (Crop Group)Project Status
13818 BENZISOTHIAZOLINONE ( NO MFG ) APPLE ( 11-10 = POME FRUIT GROUP ) IR-4 CANNOT SUPPORT AT THIS TIME

Reduced Risk Status:
IPM Compatibility: Per requestor: Very Good Fit; Benzisothiazolinone developed the same level of efficacy during a two year trial in Connecticut. No phytotoxicity was observed. Streptomycin resistant E. amylovora is susceptible to Benzisothiazolinone. Therefore, benzisothiazolinone has potential to be used as alternative to streptomycin in pesticide resistance management. Benzisothiazolinone is registered as a plant disease management material in other countries such as China;
Reasons for need: Erwinia amylovora, a bacterial pathogen and causal agent of fire blight disease. Materials that are effective for bacterial disease control is extremely limited. Fire blight is a significant issue that kills apple trees every year. Streptomycin and oxytetracycline are the most widely used materials, however, the pathogen developed resistance to these antibiotics. Streptomycin resistant E. amylovora strains were isolated in all major apple producing regions throughout the U.S;
Requesting State(s): CT:Zeng, Q* ;
PCR Use Pattern:
EPA Default Residue Trials: 1-4 2-2 5-3 9 10 11-5
IR-4 Residue Trial Plan:
Residue Protocol Use Pattern:
Efficacy/Crop Safety (E/CS) Data Required:
E/CS Research Comments:
Label Use Pattern Submitted To EPA:
EPA PIF Status:
EPA Status:
EPA PRIA Date:
MRID:
Comments: Under Eval updated by IR-4 to "IR-4 Cannot Support at This Time", since this is not an official pesticide, but rather a pure chemical, and is not supported under the Residue & Product Performance IR-4 platforms:06/24/sb
International Status:
Archive Location:
QA Archive:

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