| Reduced Risk Status: |
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| IPM Compatibility: |
Per Requester: Very Good Fit; Varada’s RNAi-based biopesticides are an ideal fit for Integrated Pest Management (IPM) programs because they offer a highly targeted mode of action that disrupts specific genes in plant pathogens without harming beneficial organisms, pollinators, or the surrounding ecosystem. Unlike conventional chemicals, these biodegradable products leave no harmful residues and degrade quickly in the environment, making them compatible with organic practices and residue-sensitive markets. By introducing a novel, non-toxic control tool, Varada’s RNAi technology supports resistance management and reduces reliance on synthetic pesticides, aligning well with the goals of sustainable, science-driven crop protection. Their flexibility across crops and compatibility with other biological and cultural methods makes them a valuable addition to any modern IPM strategy:07/25
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| Reasons for need: |
Powdery mildew (Erysiphe necator). Powdery mildew remains a top challenge in viticulture, requiring repeated fungicide use that can drive resistance, leave harmful residues, and face tightening regulatory limits. RNAi biopesticide offers a new mode of action, fits within IPM frameworks, and supports the needs of growers and exporters seeking residue-free alternatives:07/25;
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| Requesting State(s): |
CA:Eskalen, A* ;
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| PCR Use Pattern: |
Apply as a foliar spray up to 7 times every 7 days. Rates should be provided by the MFG.
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| EPA Default Residue Trials: |
1-2 10-8 11/12-2
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| IR-4 Residue Trial Plan: |
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| Efficacy/Crop Safety (E/CS) Data Required: |
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| E/CS Research Comments: |
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| Label Use Pattern Submitted To EPA: |
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| EPA PRIA Date: |
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| MRID: |
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| Comments: |
this request is for Double stranded RNAi, and requester mentioned field and greenhouse;
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| International Status: |
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| QA Archive: |
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